X-Ray Powder Diffraction: Pharmaceutical Solid-State Characterization

X-Ray Powder Diffraction (XRPD) is an essential technique in the pharmaceutical sciences. Pharmaceutical Solid-State Characterization includes applications like positive material identification, quantification of APIs and excipients, and determination of degree of crystallinity or amorphous. Because diffraction relies on long-range ordering within a material, XRPD can provide insights into structural polymorphism, supplementing the molecular information gathered from NMR and spectroscopic techniques.

This webinar will explore the topic of Pharmaceutical Solid-State Characterization, and how the Bruker D2 PHASER Benchtop XRD delivers data quality and collection speed that, up to recently, was thought impossible with a benchtop XRD system. Due to its compact size, low weight, and ease-of-use design, the system is conveniently mobile, without the need for complicated infrastructure, large, heavy-load work benches, or vendor installation and alignment. A standard power outlet and a few minutes are all that is required to take they system from fully packaged to outstanding results.

The D2 PHASER is a portable desktop XRD instrument for pharmaceutical solid-state characterization, research and quality control. It is for instance possible to investigate crystal structures applying the fundamental parameters approach in the TOPAS software, nano-structures for fast and reliable SAXS measurements, or micro-structures (crystallite size).

Key webinar takeaways:

• Overview of X-Ray Powder Diffraction
• Common instrument geometries
• Best practices for sample preparation
• Examples of data analysis examples